Erhaltungstherapie mit Methadontabletten - Eine Übersicht
Erhaltungstherapie mit Methadontabletten - Eine Übersicht
Blog Article
Methadone contains methadone, a mu-agonist opioid with an abuse liability similar to other opioid agonists and is a Schedule II controlled substance. Methadone and other opioids used in analgesia have the potential for being abused and are subject to criminal diversion.
Several factors complicate the Exegese of investigations of the children of women Weltgesundheitsorganisation take methadone during pregnancy. These include the maternal use of illicit drugs, other maternal factors such as nutrition, infection, and psychosocial circumstances, limited information regarding dose and duration of methadone use during pregnancy, and the fact that most maternal exposure appears to occur after the first trimester of pregnancy. Hinein addition, reported studies generally compare the benefit of methadone to the risk of untreated addiction to illicit drugs; the relevance of these findings to pain patients prescribed methadone during pregnancy is unclear.
There are conflicting reports on whether SIDS occurs with an increased incidence in infants born to women treated with methadone during pregnancy.
Most cases involve patients being treated for pain with large, multiple daily doses of methadone, although cases have been reported hinein patients receiving doses commonly used for maintenance treatment of opioid addiction.
After stopping treatment with methadone hydrochloride tablets, flush the unused tablets down the toilet.
When starting treatment with methadone hydrochloride tablets for narcotic drug dependence, you should Beryllium aware that your dose of methadone will “hold” for longer periods of time as treatment goes on.
Methadone belongs to a class of drugs called opioids (narcotics). A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Methadone differs from many other opioid agonists hinein several important ways. Methadone's pharmacokinetic properties, coupled with high interpatient variability hinein its absorption, metabolism, and relative analgesic potency, necessitate a cautious and highly individualized approach to prescribing. Particular vigilance is necessary during treatment initiation, during conversion from one opioid to another, and during dose titration. While methadone's duration of analgesic action (typically 4 to 8 hours) hinein the Rahmen of single-dose studies approximates that of morphine, methadone's plasma elimination half-life is substantially longer than that of morphine (typically 8 to 59 hours vs.
Do not drive, operate heavy machinery, or do other possible dangerous activities until you know how methadone hydrochloride tablets affect you. Methadone hydrochloride tablets can make you sleepy. Ask your doctor when it is okay to do these activities.
These can be symptoms that you have taken too much (overdose of) methadone hydrochloride tablets, or the dose is too high for you. They can also Beryllium symptoms of a serious heart reaction. These symptoms can lead to serious problems or death if not treated right away.
During pregnancy a woman's methadone dose Methadontabletten online zu verkaufen may need to be increased, or their dosing interval decreased. Methadone should Beryllium used rein pregnancy only if the potential benefit justifies the potential risk to the fetus.
Methadone hydrochloride tablets may not be right for you. Before starting methadone hydrochloride tablets, tell your doctor about all your medical and mental conditions including a history of drug or alcohol abuse or addiction.
Methadone may be expected to have additive effects when used in conjunction with alcohol, other opioids or CNS depressants, or with illicit drugs that cause central nervous Organisation depression. Deaths have been reported when methadone has been abused hinein conjunction with benzodiazepines.
Primary attention should Beryllium given to the reestablishment of adequate respiratory exchange through Prämie of a patent airway and institution of assisted or controlled ventilation. If a non-tolerant person, takes a large dose of methadone, effective opioid antagonists are available to counteract the potentially lethal respiratory depression. The physician must remember, however, that methadone is a long-acting depressant (36 to 48 hours), whereas opioid antagonists act for much shorter periods (one to three hours).